Clinical trials on humans have begun in China for a potential coronavirus vaccine developed by German pharmaceutical group BioNTech with Chinese company Fosun Pharma, the companies said Wednesday.Seventy-two participants have already received their first dose following approval for the phase 1 trial from Chinese regulatory authorities, BioNTech and Fosun Pharma said in a statement.The vaccine candidate, known as BNT162b1, is one of four based on BioNTech’s proprietary mRNA technology. Another, BNT162b2, is being evaluated in a global phase 3 trial conducted by BioNTech and US giant Pfizer which started on July 27.The phase 1 trial in China involves 144 participants who will receive two doses 21 days apart.Those aged 18-55 will be the first to take part, followed by older people.Laboratories around the world are racing to find a vaccine to curb COVID-19, which has claimed more than 700,000 lives and upended the livelihoods of millions. More than 200 candidate vaccines are currently being developed with roughly two dozen at the stage of clinical trials with human volunteers.Several Chinese companies are at the forefront of the global vaccine race, while Russia has said it hopes to be the first in the world to produce a vaccine for the public, with a target date of September.But the medicines will likely face heightened scrutiny given that the regulatory systems in both countries are far more opaque than they are in the West. On top of the BioNTech/Pfizer candidate, two other Western coronavirus vaccines are in final phase three trials: one produced by US biotech firm Moderna and the National Institutes for Health; and the other by the University of Oxford and Britain’s AstraZeneca. Topics :
The explosive bats of The Lions of Rushville in the first inning was too much for the Bulldogs to overcome and were defeated last night by a score of 17-7 in six innings. The Lions tallied 8 runs in the first inning with 3 singles, 3 doubles, a home run, a walk and 2 errors on the Bulldogs.The Bulldogs scored 1 run in the 3rd inning, 2 in the 4th, 3 in the 5th and 1 in the 6th. Emma Belter (single, double), Paige Oldham (single, double), and Kylie Laker (2 doubles) led the offense for the Bulldogs with 2 hits each.Paige Oldham (6) and Kara Obermeyer (4) led the defense with a combined 10 putouts.With the loss, the Bulldogs are 4-11 on the season and 2-9 in the EIAC.Courtesy of Bulldogs Coach Randy Obermeyer.The JV Lady Bulldogs were defeated Tuesday evening by a score of 9-1 to the visiting East Central Lady Trojans. The game was close most of the way until the Trojans were able to put up 4 in the top half of the sixth inning to put the game out of reach. The JV Bulldogs lone run came in the bottom of the first when Sarah Ripperger singled to right field and advanced to second on the throw. Ripperger then stole third and an errant throw allowed her to scamper home.Ripperger and Anna Gerth had the two hits on the evening for the Bulldogs.Morgan Biggs went all 6 innings on the mound in the loss; striking out 3 Trojans while scattering 12 hits.Batesville JV Softball will next be in action Thursday evening as they will travel to Greensburg to take on the Lady Pirates. First pitch will be immediately following the varsity game.Courtesy of Bulldogs Coach Stacey Kessens.
Miami women’s basketball coach Katie Meier revealed Monday that she was on a recruiting trip to Spain when the coronavirus scare began seriously gripping the globe last month, and immediately returned to South Florida for a two-week period of self-quarantine.Miami has an incoming freshman for next season from Spain, Paula Fraile Ruiz. And Europe has been a major part of Meier’s recruiting strategies for many years, so she went to Spain shortly after the Hurricanes were ousted from the ACC Tournament.Most of her meetings and visits were canceled. She left about a day after arriving, and one player she was in contact with was getting alerts on her phone about the severity of the pandemic during her meeting with Meier.“And I said, ‘OK, I need to go,’” Meier said. “I had two more visits planned, but I didn’t make them and got back.”Meier was planning to be in New York this weekend to support Miami’s Beatrice Mompremier at the WNBA draft, though that trip was canceled because of the pandemic, as well. The draft will be done remotely as planned. April 13, 2020 ___The Premier Lacrosse League has postponed the start of its 2020 season due to the ongoing COVID-19 pandemic. The season was scheduled to begin play on May 29 at Gillette Stadium in Foxborough, Massachusetts. The PLL plans to announce an update in May on a new start date for the season. “The health of our players, coaches, fans and colleagues are of paramount importance to us as we go through this unprecedented time,” Mike Rabil, who founded the league with his brother Paul, said in a statement. “As a league, we will continue to adhere to guidelines administered by the CDC, respective state governments, and our hosting venues. This was a difficult decision for our league but a necessary measure to ensure the safety of all parties.” The league debuted last year with six teams traveling to different cities to play weekend games. One team was added for this season, which has 12 weekends of regular season action planned, including an all-star game, before its playoffs. Share This StoryFacebookTwitteremailPrintLinkedinRedditThe Latest on the effects of the coronavirus outbreak on sports around the world:___Six Milwaukee Brewers players and longtime team broadcaster Bob Uecker are contributing to a $1 million fund that the franchise has established to assist game-day workers at Miller Park who have lost wages due to the coronavirus pandemic. This is the second time in four years the Browns have changed uniforms. The new ones are expected to embrace concepts from previous versions. The team is not expected to make any major changes to its iconic orange logo-less helmet.___Premier League club Tottenham has reversed a decision to use government money to fund some staff salaries during the coronavirus pandemic.The north London club faced two weeks of criticism for deciding to use the government’s job retention scheme.Tottenham chairman Daniel Levy says “the criticism the club has received over the last week has been felt all the more keenly because of our track record of good works and our huge sense of responsibility to care for those that rely on us.” David Goffin, John Isner, Karen Khachanov, Eugenie Bouchard, Kristina Mladenovic and Kiki Bertens will also participate from their homes in the April 27-30 online competition that is expected to be broadcast live on TV and social media channels.Khachanov says “this initiative is interesting and it will bring back some competition in our sport. I’m looking forward to challenge my fellow players and show my skills to the tennis fans around the world.”There will be 150,000 euros ($164,000) distributed in prize money for each of the men’s and women’s events. The winners then decide how much they want to donate to tennis players who are having a hard time financially without any tournaments to play.Another 50,000 euros ($55,000) will be donated to reduce the social impact of the pandemic.Each draw is expected to have 16 players competing. The Latest: Brewers players, Uecker give to worker fund The National Lacrosse League last week canceled the last three weekends of its regular season. The league says returning for its playoffs will be determined “based on the COVID-19 circumstances.”___The Cleveland Browns will donate net proceeds from sales of their new jerseys to a fund aiding health care professionals, first responders and others who have selflessly served during the COVID-19 pandemic.The team launched the Hats Off to Our Heroes Fund on Monday, two days before it will reveal the new uniforms. The Browns said the team will commit 100 percent of the proceeds “for a significant period of time” to the fund.“When finalizing our uniform announcement, we realized we had an incredible opportunity to further our support of heroes battling COVID-19 on the front lines for our entire community,” executive vice president JW Johnson said. “We hope the excitement surrounding the new uniforms can help make a significant impact through the Hats Off to Our Heroes Fund, and we greatly appreciate the support from our fans, retail partners and team to make this special way to give back to those leaders possible.” Associated Press Outfielder/first baseman Ryan Braun was the first to commit by providing a $100,000 pledge to the fund. Uecker followed with a $50,000 pledge. Outfielders Lorenzo Cain and Christian Yelich and pitchers Corey Knebel, Josh Lindblom and Brent Suter provided additional pledges to bring the total to $300,000.Braun and Yelich already had teamed with 3rd Street Market Hall to help provide thousands of meals to Milwaukee-area health care providers working with four major hospital networks during the pandemic.___The Spanish league says it will not attend upcoming meetings organized by the Spanish Football Federation to discuss the effects of the coronavirus pandemic.The league says the decision is a response to the federation’s release to the media of audios from a previous meeting to allegedly boost its own interests. The Madrid Open was one of more than 30 professional tournaments canceled or postponed because of the coronavirus pandemic. It had been scheduled for May 1-10.___Spanish soccer club Real Sociedad is going back on its plan to resume practicing at the team’s training center during the coronavirus pandemic.The club says it made the decision after discussions with the Spanish government. It says it is “fully aware of its responsibility during the current pandemic” and “players will continue to train at home.”Real Sociedad had said it would give its players the option to start training individually at the team’s training center beginning on Tuesday. It would be the first Spanish club to return to practice during the pandemic. The league says it will take the necessary legal actions against the federation for having released the information without anybody else’s consent. Spain’s players’ association had already said it would sue the federation because of the audios that undermined its president.The federation admits it released the recordings but denies they were leaked. It says it was clear to everyone that the conversations would be recorded.The federation, the league, and the players’ association have been at odds over a variety of issues in recent years and the disputes have continued during the pandemic despite their own calls for unity. ___ Staff put on furlough during the pandemic receive 80% of their salaries up to a maximum of 2,500 pounds ($3,000) per month from the government. And Tottenham had said non-playing staff not being furloughed would have their pay cut 20%.But Levy now says “in the context of revised budgets and cost cutting” all non-playing staff will remain on full pay in April and May with only the board having salaries reduced.The Premier League season has been suspended for more than a month with no date set for its resumption.___Rafael Nadal and Andy Murray are among 12 players confirmed to play in the virtual Madrid Open tennis tournament this month. Spain is starting to loosen some of its lockdown measures this week by allowing non-essential workers to return to their activities while observing social-distancing guidelines. But group activities will remain prohibited and sports facilities won’t be allowed to reopen.Real Sociedad says players have been training at home for the last month. The club prepared individual training routines for players and sent them stationary bicycles and treadmills.___More AP sports: https://apnews.com/apf-sports and https://twitter.com/AP_Sports
In an effort to offer a guide for the division of archaeological sites between Israel and Palestine in the event of a peace agreement, the USC Digital Library earlier this week presented the first public map of the sites based on research commissioned by a USC professor and other researchers.The West Bank and East Jerusalem Searchable Map, using a Google map interface, on the library’s website, includes the names, locations, components and periods of nearly 7,000 archaeological sites in the contested region.Border crossing · Lynn Dodd, a project leader for the West Bank and East Jerusalem Searchable Map, examines an ancient Egyptian gravemarker with senior Jenny Crawford. – Dieuwertje Kast | Daily TrojanThe map was an initiative of the Israeli-Palestinian Archaeology Working Group, which includes Lynn Dodd, a lecturer of religion at USC, curator of the USC Archaeology Research Center and one of the project leaders; Ran Boytner, director of international research at the UCLA Cotsen Institute of Archaeology; and a team of prominent Israeli and Palestinian archaeologists and negotiators.The group was created in 2005 to negotiate a plan on how to govern the archaeological sites in Israel and Palestine if a peace deal is brokered between the two sides.“You cannot get a good divorce unless you know who has what,” Boytner said. “Now, when the negotiators are talking about dividing the border, they will have that information.”Dodd and Boytner, who met as graduate students at UCLA, said they began the project after discovering that, unlike other issues like refugees and the fate of Jerusalem, nothing had been done to address the archaeological sites in the region.“We realized that there was no way anyone could negotiate terms for archaeology because the records didn’t exist,” Dodd said. “The last 40 years of Israeli archaeology in the occupied territory was not publicly available.”Dodd said she believes the map fills a void in the painting of a complete picture of not only Israel, but also the surrounding countries of Jordan and Syria. Without the map, she said, it would be impossible to write the history of archaeology in the region.“It’s like trying to write the history of early colonial America with only information about eight colonies,” Dodd said. “There’s a huge hole. [The map] is a valuable resource if you’re trying to paint a complete picture of archaeology in this part of the world.”The Israeli-Palestinian Archaeology Working Group collaborated with two researchers, Rafi Greenberg of Tel Aviv University and Adi Keinan of the University College London, to conduct research and collect data for the map of the archaeological sites. The research group was initially denied the information and sued the civil administration of the Israeli province in order to gain access to it.After winning the suit and collecting the data, Dodd worked with Matt Gainer, director of the USC Digital Library and its information technology department to provide an avenue for everyone to view the data through the Google map.“We are able to make the content available in a non-partisan environment — opening it up for broad inquiry and objective consideration,” Gainer said.In recognition of this transparency and the political relevance of the map, the group won the 2009 ASOR Open Archaeology Prize from the American Schools of Oriental Research earlier this month. Ashley Sands, an alumna who worked with Dodd as an undergraduate studying archaeology, said the openness of the project sets it apart.“One of the complaints I’ve heard from colleagues is that researchers have not been transparent with their work,” said Sands, who also co-founded a student group that discusses the relationship between archaeology, heritage and politics, with Dodd’s help. “The fact that this project was published for everyone to see directly combats that problem.”The map is still a work in progress, according to Dodd, who plans to develop PowerPoint slides to give greater detail of the individual sites and eventually make the database downloadable.For now though, Dodd said she is just happy that they were able to pull off the project after the obstacles they faced in collecting and presenting the data.“We pulled together Israelis and Palestinians and created this resource so that it would help safeguard the archaeological heritage for the Israelis, for the Palestinians, and for everybody else,” she said.
HOUSTON — It seems that Justin Upton’s All-Star break has started early.Upton was not in the lineup for the third straight game on Saturday, and he said the plan is to give him Sunday off, too, which will allow him more than a week for his tight left quad to improve.Upton, who came out of Wednesday’s game with the injury, said he felt “good” on Saturday, but the team wouldn’t even let him try to run.“At this point they want to give me as much time as they can,” Upton said Saturday. “With the break right around the corner, they think if they err on the cautious side, when Friday comes around I won’t have any issues.” Upton missed the first two and a half months of the season with a sprained toe. Since returning, he hit .269 with three homers and an .806 OPS.“I felt great,” Upton said. “I was putting the ball in play and giving myself a chance. Obviously, it’s a round bat, round ball, so you can mis-hit some balls. For the most part, I feel like I’m making good swings.”LEADOFF SHUFFLETommy La Stella’s injury has left the Angels with a question mark in the leadoff spot.Manager Brad Ausmus indicated earlier in the week that he would likely have Kole Calhoun bat leadoff against righties and David Fletcher against lefties. However, on Saturday he put Fletcher at the top against a righty, with Calhoun in the cleanup spot.Ausmus normally wouldn’t want the left-handed hitting Calhoun to bat behind Shohei Ohtani, also a lefty, but the Houston Astros don’t currently have a lefty in their bullpen. He also put lefties Justin Bour and Jarrett Parker back-to-back. Angels offense breaks out to split doubleheader with Astros Jose Suarez’s rocky start sinks Angels in loss to Astros Angels’ Mike Trout working on his defense, thanks to Twitter The Angels leadoff spot could eventually go to Luís Rengifo, who profiles almost perfectly for that job. He’s a switch hitter with speed and he is disciplined at the plate.Lately, Rengifo has been particularly hot. He came into Saturday’s game hitting .328 with a .397 on-base percentage in his previous 18 games.Ausmus said Rengifo has improved lately, especially in his plate discipline, but he’d still like to keep him at the bottom of the order because of his inexperience. He was playing in his 51st big league game on Saturday.“He’s getting comfortable at the major league level,” Ausmus said.Related Articles ALSOJC Ramírez will have at least one more rehab outing at Triple-A Salt Lake on Thursday, Ausmus said. Ramírez, who has nearly completed his rehab from Tommy John surgery, gave up three runs in six innings on Friday night, after allowing two runs in five innings in his previous start. Even if the Angels believed Ramírez was ready for the majors now, they could have him pitch again at Triple-A because the All-Star break pushes back the need for him in the majors…Keynan Middleton, who is also coming back from Tommy John surgery, was “good,” Ausmus said, in his the first game of his rehab, on Friday night. Middleton pitched in the Arizona League on Friday night, but he is likely to move up to Class-A Inland Empire next, Ausmus said.UP NEXTAngels (LHP José Suarez, 2-1, 5.40) at Astros (RHP José Urquidy, 0-0, 4.91), 11:10 a.m. PT, Fox Sports West Angels’ poor pitching spoils an Albert Pujols milestone Angels’ Shohei Ohtani spending downtime working in outfield Newsroom GuidelinesNews TipsContact UsReport an Error
DES MOINES — The leader of a House committee is promising to block any attempt to adjust the pension benefits awarded through the Iowa Public Employees Retirement System — commonly called IPERS.Republican Representative Bobby Kaufman of Wilton is chairman of the House State Government Committee, the panel that would consider any IPERS policy changes.“There is very simply and unequivocally not going to be changes,” Kaufmann said Tuesday.A Republican state senator introduced a bill last year that would have enrolled future state and local government employees into something like the 401k systems available in the private sector. Kaufmann said if that idea is resurrected in the state senate, it will go nowhere in the Iowa House and groups that are saying otherwise are wrong.“All these groups that are pushing out this crap, after today what you are doing will be completely deceitful, so I want to make it crystal clear,” Kaufmann said. “Republicans never had intentions of taking away or substantively changing your IPERS and going forward over the next two years unequivocally there will be none.”Representative Mary Mascher, a Democrat from Iowa City, said because Republicans made dramatic changes to Iowa’s collective bargaining law in 2017, there’s a “lack of trust” when Republicans make pledges about public workers’ pensions.“I appreciate the fact that you’re very adamant about making no changes and I think that’s important,” Mascher said during Tuesday’s committee meeting, “but that message needs to be delivered to the senate, because they have been proposing legislation.”Kaufmann replied that no bill becomes law without coming through the Iowa House.“It is absolute that after today, any group that sends out the email scaring our constituents, I’m going to publicly call you a liar,” Kaufmann said.Progress Iowa is one of the group’s Kaufmann specifically cited Tuesday. The group’s executive director in a written statement said retirement security is “too important for us to stay silent” and his group “won’t be bullied by Bobby Kaufmann.”